1、个人照片

2、基本信息：

欢迎广大热爱科研有志于从事污染物在环境中归趋、污染物毒性评价及致毒机理分析的同学报考！

3、个人简介

博士毕业于柏林洪堡大学应用分析与环境化学专业，并在同一课题组做了一年博后，然后就职bwin，主要从事新型污染物的致毒机理、污染物在环境中的转化、归趋及毒性评价，氧化过程中中间产物的鉴定及毒性评价

3.1 教育经历：

(1) 2010-10 至 2015-02, 柏林洪堡大学，应用分析与环境化学，博士

(2) 2007-09 至 2010-07, 湖南大学，环境工程，硕士

(3) 2002-09 至 2006-07, 安徽农业大学，环境科学，学士

3.2 工作经历

(1) 2016-4至今，bwin，bwin，副教授

(2) 2015-3至2015-12，柏林洪堡大学，博士后，导师：Michael W. Linscheid

3.3曾获荣誉

(1) 2017年入选江苏省“双创博士”人才计划

(2) 2015年德国学术交流中心（DAAD）博士论文写作奖

4、学术兼职或社会兼职

(1) 2019-至今, 中国环境科学学会会员

(2) 2019年至今, 环境毒理及化学学会会员（SETAC）

(3) 2018-至今, 国际水协会员（IWA）会员

(4) 2012年至今, 德国质谱学会会员（DGMS）会员

(5) 2011年至今, 留德华人化学与化工学会会员

担任Water Research, Environmental Science & Technology, Aquatic Toxicology等权威期刊的审稿人。

5、科研项目

1、江苏省自然科学基金，筛选诊断卡马西平环境污染的特异性生物标志物, 20万，结题，主持

2、合成水中低碳含氧有机物高效提取与水资源化技术开发及中试验证，“十三五”国家重点研发，475万，结题，参与

3、国际合作培育项目，bwin，自由选题，2万，结题，主持

4、南京市留学归国人员优先资助项目B类， 加巴喷汀及其降解产物对水生生物制毒机理研究，3万，结题，主持

5、国家自然科学基金青年项目，Yap与Hedgehog信号在激活HSC诱发肝纤维化中的相互作用机制探索， 25万元，结题，参加

6、国家自然科学基金青年项目,厌氧脱溴菌群降解多溴联苯醚的脱卤呼吸，25万，在研，参加

7、基于生物效应导向分析筛选化工废水主污染因子, 企业委托, 6.8万元, 结题, 主持

8、国际创新团队培育项目，3万，校内项目，在研，主持

9、典型难降解污染物在自然水体中的毒性转化机理，6万，在研，主持

10、科技部项目，气候变化叠加典型污染因子对我国近海蛤类可持续利用的影响，20万，在研，主持

11、自然科学基金面上项目，硫酮噻/咪唑类物质对蛙类甲状腺干扰作用和异噻唑啉酮类杀菌剂对其增敏的机制研究，46万，在研，主持

6、代表性成果

论文：

(1) Yide He, Jun Hu Rosa Freitas, Jie Gu, Guixiang Ji, Yongjun Zhang, Trace-level Gabapentin can Induce Cardiovascular Developmental Toxicity through Apoptosis in Zebrafish Larvae, Environmental Pollution, 2024 (358), 124526

(2)Y. He, Y.Zhang, W. Zhou, R. Freitas, Y.Zhang, Y. Zhang*, , “Combined exposure of polystyrene microplastics and carbamazepine induced transgenerational effects on the reproduction of Daphnia magna”, Environmental Science and Pollution Research, 2023, 30, 67596–67607

(3) W. Zhou, Z. Qin, Y. Li, J. Li, Y. Li, M. Dong, X. Li, Y. Zhang*, Y. He*, “Methimazole and sodium perchlorate exert anti-thyroidal effects in the T3-induced Xenopus laevis metamorphosis assay: A rapid assay for screening thyroid disrupting chemicals”, Aquatic toxicology, 2023, (257), 106431.

(4) P. Cruz, A. Cuccaro, C. Pretti, Y. He, A. M.V.M. Soares, R. Freitas*,Comparative subcellular responses to pharmaceutical exposures in the mussel Mytilus galloprovincialis: An in vitro study, Environmental Toxicology and Pharmacology,Volume 104,2023,104314,ISSN 1382-6689,https://doi.org/10.1016/j.etap.2023.104314.

(5) S. Paciello,T. Russo, L. Marchi , A. Soares, V. Meucci,C. Pretti, Y. He, C. Torre, R. Freitas*. Sub-lethal effects induced in Mytilus galloprovincialis after short-term exposure to sodium lauryl sulfate: Comparison of the biological responses given by mussels under two temperature scenarios. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2023,270:109644.

(6)Y. He^*, R. Zhu, W. Zhou, Y. Zhang, Y. Zhang, S. Pan, R. J.Schneider, Y. Zhang^*,” Transcriptomics and protein biomarkers reveal the detoxifying mechanisms of UV radiation for nebivolol toward zebrafish (Danio rerio) embryos/larvae”, Aquatic toxicology, 2022, (249), 106241.

(7) Y. He, Y. Cai, S. Fan, T. Meng, Y. Zhang, X. Li^*, Y. Zhang^*, ” Hydroxyl Radicals Can Significantly Influence the Toxicity of Ofloxacin Transformation Products During Ozonation”, Journal of Hazardous Materials, 2022, 438, 129503.

(8) T. Liu, Y. Lawluvy, Y. Shi, J. O. Ighalo, Y. He, Y. Zhang, P-S. Yap^*, ”Adsorption of cadmium and lead from aqueous solution using modified biochar: A review”, Environmental Chemical Engineering,2022,10(1),106502.

(9) J. Lu, J. Wu, L. Gong, Y. Cheng, Q.Yuan^*, Y. He^*, ”Combined toxicity of polystyrene microplastics and sulfamethoxazole on zebrafish embryos”, Environmental Science and Pollution Research, 2021:1-10.

(10) S. Du, R. Zhu, Y. Cai, N. Xu, P-S. Yap, Y. Zhang, Y. He^*, Y. Zhang^*, ”Environmental fate and impacts of microplastics in aquatic ecosystems: a review”, RSC Advances, 2021, 11, 15762.

(11) Y.He, D. Jia, S. Du, R. Zhu, W. Zhou, S. Pan, Y. Zhang^*, ”Toxicity of gabapentin-lactum on the early developmental stage of zebrafish (Danio rerio)”, Environmental Pollution, 2021, 287, 117649.

(12) D. Jia, X. Li, S. Du, N. Xu, W. Zhang, R. Yang, Y. Zhang, Y. He^*, Y. Zhang^*, ”Single and combined Effects of carbamazepine and copper on nervous and antioxidant systems of zebrafish (Danio rerio)”, Environmental Toxicology, 2020, 35(10), 1091-1099.

(13) Z. Du, K. Li, S. Zhou, X. Liu, Y. Yu, Y. Zhang, Y. He^*, Y. Zhang^*, ”Degradation of ofloxacin with heterogeneous photo-Fenton catalyzed by biogenic Fe-Mn oxides”, Chemical Engineering Journal, 2020, 380, 122427.

(14) Y. Yu, F. Huang^*, Y. He, F. Wang, Y. Lv, Y.Xu & Y.Zhang^* ,” Efficient degradation of sulfamethoxazole by catalytic wet peroxide oxidation with sludge-derived carbon as catalysts”, Environmental Technology, 2020,41(7), 870-877

(15) Z. Zhang, Y. Yu, F. Huang^*, X. Yi, Y. Xu, Y. He, J. B. Baell, and H.Huang^*,”Catalytic O–H bond insertion reactions using surface modified sewage sludge as a catalyst”, Green Chemistry, 2020, 22,1594.

(16) Y. Zhang, S. Zhou, X. Su, J. Xu, G. Nie, Y. Zhang, Y. He^*, S. Yu^*,” Synthesis and characterization of Ag-loaded p-type TiO2 for adsorption and photocatalytic degradation of tetrabromobisphenol A”, Water Environment Research, 2020 ,92(5):713-721.

(17) X. Liu, F. Huang, Y. Yu^*, Y. Jiang, K. Zhao, Y. He, Y. Xu, Y .Zhang^*,” Determination and toxicity evaluation of the generated byproducts from sulfamethazine degradation during catalytic oxidation process”, Chemosphere. 2019 ,226:103-109.

(18) X. Liu, F. Huang, Y. He, Y. Yu^*, Y. Lv, Y. Xu, Y. Zhang^*,”Oxytetracycline degradation and toxicity evolution by catalytic oxidation process over sludge derived carbon”,Environmental Chemical Engineering,2019,7(1),102889.

(19) X. Liu, F. Huang, Y. Yu^*, P. Zhao, Y. Zhou, Y. He, Y. Xu, Y. Zhang^*,”Ofloxacin degradation over Cu–Ce tyre carbon catalysts by the microwave assisted persulfate process”,Applied Catalysis B: Environmental,2019,253,149-159.

(20) Y. Yu, F. Huang^*, Y. He, X. Liu, C. Song, Y. Xu, Y. Zhang^*,”Heterogeneous fenton-like degradation of ofloxacin over sludge derived carbon as catalysts: Mechanism and performance”, Science of The Total Environment, 2019,654,942-947.

(21) Y. He, X. Li, D. Jia, W. Zhang, T. Zhang, Y. Yu, Y. Xu, Y. Zhang^*,”A transcriptomics-based analysis of the toxicity mechanisms of gabapentin to zebrafish embryos at realistic environmental Concentrations”, Environmental Pollution, 2019, 251, 746.

(22) C. Shi, Y. He^*, J. Liu, Y. Lu, Y. Fan, Y. Liang, Y. Xu^*,” Ecotoxicological Effect of Single and Combined Exposure of Carbamazepine and Cadmium on Female Danio rerio: A Multibiomarker Study”, Applied Sciences, 2019, 9, 1362.

(23) S. Zhou, Z. Du, X. Li, Y. Zhang, Y. He^*, Y. Zhang^*,”Degradation of methylene blue by natural manganese oxides: kinetics and transformation products”, Royal Society Open Science, 2019, 6(7), 190351.

(24) X. Li, S. Zhou, Y. Qian, Z. Xu, Y. Yu, Y. Xu, Y. He*, Y. Zhang*,” The assessment of the eco-toxicological effect of gabapentin on early development of zebrafish and its antioxidant system”, RSC Advances, 2018, 8, 22777.

(25) A.H. EI-Khatib^#, Y. He^#, D. Esteban-Fernandez, M.W. Linscheid^*,”Application of higher energy collisional dissociation (HCD) to the fragmentation of new DOTA-based labels and N-termini DOTA-labeled peptides”, Journal of Mass Spectrometry, 2017, 52(8):543-549.

(26) Y. He, D. Esteban-Fernandez, B. Neumann, U. Bergmann, F. Bierkandt, M. W. Linscheid*, ”Application of MeCAT-Click labeling for protein abundance characterization of E.coli after heat shock experiments”, Journal of Proteomics, 2016, 136, 68-76.

(27) Y. He, D. Esteban-Fernandez, M. W. Linscheid*,”Novel approach for labeling of biopolymers with DOTA complexes using in situ click chemistry for quantification”, Talanta, 2015, 134(134), 468-475.

(28) Y. He, Y. Zhai*, C. Li, F. Yang, L. Chen, X. Fan, W. Peng, Z. Fu, ” The fate of Cu, Zn, Pb, Cd during the pyrolysis of sewage sludge at different temperatures”, Environmental & Technology, 2010, 31(5), 567-574.

专利：

（1）一种纳米复合材料非均相光Fenton催化剂及其制备和应用，ZL201810935587.3，于杨;胡炼;丁石虎;黄菲;张永军;何益得;乔纳森贝尔

（2）一种高分散金属催化剂的制备方法及其应用，ZL201810934913.9，于杨;姜泳安;赵鹏;黄菲;何益得;张永军;乔纳森贝尔

（3）一种活化过硫酸盐轮胎碳催化剂及制备与应用，ZL201810935718.8，于杨;刘西扬;周园柏;黄菲;何益得;张永军;乔纳森贝尔

（4）二氧化钛和二氧化硅复合材料催化剂及制备和应用，ZL201811182900.7，于杨;周哲平;刘嘉威;黄菲;张运海;何益得;张永军;乔纳森贝尔

（5）一种板框式电芬顿反应装置，ZL202121217912.6，徐安琳;孙鑫;曹丽亚;潘顺龙;何益得;张永军

（6）一种利用废旧轮胎制备电催化气体扩散电极的方法，ZL202110067782.0，张永军；徐安琳；刘万群；孙鑫；邱雯金；龚子轩；潘顺龙；何益得